Method for improving pharmacokinetics

Details Method for improving pharmacokinetics Method for improving pharmacokinetics

A - Human Necessities

61

K

A61K 31/661 (2006.01) A61K 31/18 (2006.01) A61K 31/44 (2006.01) A61K 31/63 (2006.01) A61P 31/18 (2006.01)

Patent

CA 2657316

The present invention provides pharmaceutical compositions and methods for improving the pharmacokinetics of drugs which may be metabolized by cytochrome P450 monooxigenase, the method may comprise co-administering a compound of formula I, with the drug; when the compound of formula I comprises an amino group, pharmaceutically acceptable ammonium salts thereof, wherein R1 may be, for example, H1 (HO)2P(O)-, (NaO)2P(O)-, alkyl-CO- or cycloalkyl-CO-, wherein X may be, for example, F, Cl, and Br, and wherein R2 and R3 are as defined herein.

Compositions pharmaceutiques et procédés améliorant la pharmacocinétique de médicaments susceptibles d'être métabolisés par la monooxygénase de cytochrome P450. On décrit un procédé qui peut consister à co-administrer un composé de formule I ci-après et le médicament, ledit composé comprenant un groupe amino, des sels d'ammonium correspondants pharmaceutiquement acceptables, sachant que R1 peut être, par exemple, H, (HO)2P(O)-, (NaO)2P(O)-, alkyl-CO ou cycloalkyl-CO-, et que X peut être par exemple F, Cl et Br, et enfin que R2 et R3 sont tels que définis dans la description.

Affiliated with

Also associated with

Rating

Method for improving pharmacokinetics does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for improving pharmacokinetics, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for improving pharmacokinetics will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1692786