Phenyl-1,2,5-oxadiazolecarboxamide-2-oxides

Details Phenyl-1,2,5-oxadiazolecarboxamide-2-oxides Phenyl-1,2,5-oxadiazolecarboxamide-2-oxides

C - Chemistry, Metallurgy

07

D

C07D 271/08 (2006.01) A61K 31/42 (2006.01) A61K 31/45 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07D 413/02 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2098779

23233-281 ABSTRACT The invention relates to phenyl-1,2,5- oxadiazolecarboxamide-2-oxides of the general formula I Image (I) in which one of the radicals R1 and R2 represents Image and the other represents Image wherein R3 and R are, for example, (C1-C5)-alkyl and R and R are, independently of one another, hydrogen, (C1-C4)-alkyl, (C1-C4)-alkoxy, fluorine, chlorine, bromine, nitro or trifluoromethyl. The compounds of the formula I have useful pharmacological properties and can be used for the control and prevention of disorders of the cardiovascular system, in particular for the treatment of erectile dysfunction.

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