Improvements in or relating to formulations for use in...

Details Improvements in or relating to formulations for use in... Improvements in or relating to formulations for use in...

A - Human Necessities

61

K

A61K 9/72 (2006.01) A61K 9/14 (2006.01) A61K 31/167 (2006.01) A61K 31/573 (2006.01) A61K 31/58 (2006.01)

Patent

CA 2406206

A formulation for use in an inhaler device comprises carrier particles having a diameter of at least 50µm and a mass median diameter of at least 175µm; fine particles of an excipient material having a mass median aerodynamic diameter of not more than 20µm; and active particles. The formulation has excellent flowability even at relatively high contents of fine particles.

L'invention concerne une formulation à utiliser dans un dispositif d'inhalation, constituée de particules porteuses ayant un diamètre d'au moins 50 µm et un diamètre moyen massique d'au moins 175 µm; de fines particules d'un excipient ayant un diamètre aérodynamique moyen massique n'excédant pas 20 µm, et de particules actives. La formulation présente une excellente aptitude à l'écoulement, même à des teneurs relativement élevées de fines particules.

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