Alteration of rab38 function to modulate mammalian pigmentation

Details Alteration of rab38 function to modulate mammalian pigmentation Alteration of rab38 function to modulate mammalian pigmentation

C - Chemistry, Metallurgy

12

N

C12N 15/55 (2006.01) A61K 6/00 (2006.01) A61K 31/7088 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) A61P 17/00 (2006.01) A61P 43/00 (2006.01) C07K 14/47 (2006.01) C12N 1/15 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/09 (2006.01) C12Q 1/42 (2006.01) C12Q 1/68 (2006.01) G01N 33/15 (2006.01)

Patent

CA 2473474

The present invention relates to compositions and methods involving melanocytes. In particular, the present invention provides compositions and methods involving RAB38 and mutant RAB38, suitable for use in modulation of pigmentation and for use in determining the means to diagnose and/or treat conditions associated with disorders in pigmentation.

L'invention concerne des compositions et des procédés impliquant les mélanocytes. Plus particulièrement, l'invention concerne des compositions et des procédés impliquant RAB38 et RAB38 mutant, qui permettent de moduler la pigmentation et de déterminer les moyens pour le diagnostic et/ou le traitement des états pathologiques associés aux troubles pigmentaires.

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