Combination therapy for treatment of patients with...

A - Human Necessities – 61 – K

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A61K 36/481 (2006.01) A61K 35/56 (2006.01) A61K 35/62 (2006.01) A61K 35/64 (2006.01) A61K 36/236 (2006.01) A61K 36/537 (2006.01) A61K 36/65 (2006.01) A61K 36/69 (2006.01) A61K 36/88 (2006.01) A61P 9/04 (2006.01) A61P 25/28 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2646240

The present invention provides compositions and methods of treating a patient having a condition selected from the group of cerebral stroke, heart stroke, neurodegenerative diseases, brain or nervous system trauma, or neuroplasticity wherein the composition comprises: (i) at least 4, 5, 6, 7, 8, 9, 10, 11, 12, 13 or 14 of: Radix Astragali (milkvetch root or Huang Qi); Rhizoma Salviae Miltiorrhizae root (red sage or Dan Shen); Radix Paeoniae Rubra (red peony or chi shao); Ligusticum Chuanxiong (Chuan Xiong); Rhizoma Notoginseng (Sanqi); Odoriferous Rosewood (Jiang Xiang); Scorpion (Quan Xie); Radix Polygalae (Yuan Zhi); Grassleaf sweetflag (Shi Changpu); Leech (Hirudo or Shuizhi); Ground beetle (Tu Bie Chong); Cow bezoar (calculus Bovis artifactus or Rengong Niuhuang); Gambirplant (ramulus uncariae cum uncis or Gou teng); and (ii) an agent used in Western medicine.

La présente invention concerne des compositions et des procédés de traitement d'un patient présentant une condition choisie dans le groupe constitué par l'accident vasculaire cérébral, la crise cardiaque, les maladies neurodégénératives, les traumatismes du cerveau ou du système nerveux ou la neuroplasticité, ladite composition comprenant : (i) au moins 4, 5, 6, 7, 8, 9, 10, 11, 12, 13 ou 14 agents parmi : - Radix astragali (racine d'astragale ou Huang Qi) - Radix salviae miltiorrhizae (racine de sauge rouge ou Dan Shen) - Radix paeoniae rubra (racine de pivoine rouge ou Chi Shao) - Ligusticum chuanxiong (Chuan Xiong) - Radix notoginseng (San Qi) - Dalbergia odorifera (Jiang Xiang) - Scorpion (Quan Xie) - Radix polygalae (Yuan Zhi) - Jonc à feuilles de graminées (Shi Chang Pu) - Sangsue (Hirudo ou Shui Zhi) - Eupolyphaga seu opisthoplatia (Tu Bie Chong) - Bézoard de bovin (Calculus bovis artifactus ou Ren Gong Niu Huang) - Griffe de chat (gambir) (Ramulus uncariae cum uncis ou Gou Teng); et (ii) un agent utilisé dans la médecine occidentale.

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