Implantable device containing resorbable matrix material and...

Details Implantable device containing resorbable matrix material and... Implantable device containing resorbable matrix material and...

A - Human Necessities

61

K

A61K 31/395 (2006.01) A61K 9/00 (2006.01) A61K 31/122 (2006.01) A61K 31/337 (2006.01) A61K 31/573 (2006.01) A61K 31/727 (2006.01) A61K 38/08 (2006.01) A61K 38/13 (2006.01) A61K 47/36 (2006.01) A61K 47/42 (2006.01) A61M 1/00 (2006.01) A61M 39/10 (2006.01) A61P 43/00 (2006.01) A61M 1/16 (2006.01)

Patent

CA 2434972

A therapeutic implant, apparatus and methods useful for preventing, suppressing (inhibiting) or treating failure of hemodialysis vascular access and other vascular grafts from outside the vascular or graft lumen and through the vascular wall (extravascularly or perivascularly). The implantable device contains resorbable matrix material (e.g. collagen, fibrin, chitosan) and antiproliverative agent(s), for instance3 Rapamycin, Paclitaxel, Tacrolimus etc. and other cell cycle inhibitor or similarly-functioning agents.

L'invention concerne un dispositif prothétique généralement placé sur la surface extérieure d'un vaisseau ou un greffon permettant d'éluer des agents ou des médicaments antiprolifératifs à partir d'une matière de base d'élution de médicaments. L'invention se rapporte en outre à des méthodes d'administration périvasculaire de médicaments antiprolifératifs.

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