Food for improving clinical conditions capable of lowering...

A - Human Necessities – 61 – K

Patent

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A61K 31/715 (2006.01) A23L 1/308 (2006.01) A61P 1/16 (2006.01) A61P 13/12 (2006.01)

Patent

CA 2519761

It is intended to provide a novel food for improving clinical conditions by which shift to hemodialysis in treating renal insufficiency can be prevented or retarded, the frequency of hemodialysis can be lowered or the onset of hyperammonemia in hepatic insufficiency can be prevented or relieved. Namely, a food for improving clinical conditions, which aims at achieving the above object, characterized by containing hardly digestible polysaccharides as the main components together with a restricted amount of protein components. Taking this food for improving clinical conditions, microbial proteins are synthesized by using the energy generated by the metabolism of the hardly digestible polysaccharides and urea or ammonia secreted into the intestines as an N source and the thus proliferated microbial cells are discharged into the feces. According to this mechanism, low-molecular weight nitrogen-containing compounds in the blood can be reduced and, as a result, renal failure and hepatic failure can be ameliorated.

L'invention concerne un nouveau produit alimentaire servant à améliorer certaines conditions cliniques, ce qui permet de prévenir ou de retarder le passage à l'hémodialyse pour traiter l'insuffisance rénale, d'abaisser la fréquence de l'hémodialyse ou de prévenir ou de soulager les crises d'hyperammoniémie dans l'insuffisance hépatique. Ce produit alimentaire contient des polysaccharides faiblement digestibles en tant que constituants principaux, ainsi qu'une quantité limitée de protéines. Ce produit alimentaire permet de synthétiser les protéines microbiennes au moyen de l'énergie générée par le métabolisme de ces polysaccharides, l'urée ou l'ammoniaque sécrétés dans les intestins en tant que source d'azote et la prolifération des cellules microbiennes étant évacués dans les sels. Ce mécanisme permet de réduire les composés sanguins de poids moléculaire faible contenant de l'azote et, par conséquent, d'améliorer les insuffisances rénales et hépatiques.

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