Pyridotriazines and pyridopyridazines

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 487/04 (2006.01) A61K 31/50 (2006.01) A61K 31/53 (2006.01) A61P 35/00 (2006.01) C07D 471/04 (2006.01) C07D 487/02 (2006.01)

Patent

CA 2356544

This invention relates to bicyclic heterocycles that inhibit cyclin-dependent kinase or tyrosine kinase enzymes, or both, and as such are useful to treat cell proliferative disorders such as angiogenesis, atherosclerosis, restenosis, and cancer as well as immunological disorders such as asthma, rheumatoid arthritis, autoimmune diabetes, and graft rejection associated with transplant surgery in mammals.

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