The preparation of n-protected n-alkylated amino acids

C - Chemistry – Metallurgy – 07 – C

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C07C 271/22 (2006.01) C07C 269/06 (2006.01) C07C 319/20 (2006.01) C07C 323/57 (2006.01) C07D 209/48 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2157802

The description relates to a process for producing N-protected N-alkylated amino acids of formula (1), in which Rs and R1 to R3 have the meanings given in the description, in which a compound of said formula (1), wherein R3 is a hydrogen atom, is added to a solution of a base in a non-protic solvent which is then mixed with an alkylising agent.

On décrit un procédé pour la préparation d'acides aminés à protection N et alkylation N de formule (1), dans laquelle R?s¿ et R?1¿-R?3¿ ont la signification donnée dans la description, procédé qui consiste à ajouter un composé de ladite formule (1), dans laquelle R?3¿ est un atome d'hydrogène, à une solution d'une base dans un solvant non protique que l'on mélange ensuite avec un agent alkylant.

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