Pharmaceutical compositions containing venlafaxine

Details Pharmaceutical compositions containing venlafaxine Pharmaceutical compositions containing venlafaxine

A - Human Necessities

61

K

A61K 9/28 (2006.01) A61K 31/135 (2006.01) A61K 31/137 (2006.01) C07C 217/74 (2006.01)

Patent

CA 2503380

The invention provides a delayed burst release formulation comprising a core formed as a compressed tablet and an outer coating that surrounds the core; said core comprising venlafaxine, or a pharmaceutically acceptable salt thereof, at least one burst controlling agent and a disintegrant; and said outer coating comprising a water insoluble hydrophobic carrier and water- insoluble but hydrophilic particulate matter.

L'invention concerne une formulation retard à libération progressive comprenant un noyau présenté sous la forme d'une pastille comprimée et un enrobage externe entourant le noyau renfermant la venlafaxine ou un sel acceptable sur le plan pharmaceutique de celle-ci, au moins un agent de commande de décharge et un désintégrant; l'enrobage externe comprenant un véhicule hydrophobe insoluble dans l'eau et une matière particulaire insoluble dans l'eau mais hydrophile.

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