Substituted piperidino-dihydrothienopyrimidines

Details Substituted piperidino-dihydrothienopyrimidines Substituted piperidino-dihydrothienopyrimidines

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/519 (2006.01) A61P 11/00 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2705414

The invention relates to the novel piperidino-dihydrothienopyrimidines of formula (I) and to the pharmacologically acceptable salts thereof, wherein X represents SO or SO2, preferably however SO, and wherein R1, R2, R3 and R4 are defined as in claim 1. The invention also relates to pharmaceutical compositions containing said compounds. The novel piperidino-dihydrothienopyrimidines are suitable for use in the treatment of respiratory or gastrointestinal disorders or diseases, inflammatory diseases of the joints, the skin or the eyes, diseases of the peripheral or central nervous system or cancers.

L'invention concerne de nouvelles pipéridino- dihydrothiénopyrimidines de formule (1), ainsi que leurs sels pharmacologiquement compatibles. Dans la formule, X représente SO ou SO2, de préférence SO, et R1, R2, R3 et R4 ont la signification indiquée dans la revendication 1. L'invention concerne également des compositions pharmaceutiques contenant ces composés. Ces nouvelles pipéridino- dihydrothiénopyrimidines sont appropriées pour le traitement des troubles ou des affections des voies respiratoires ou gastro-intestinales, des maladies inflammatoires des articulations, de la peau ou des yeux, des maladies du système nerveux périphérique ou central ou des maladies cancéreuses.

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