Method for preparing chiral amines

Details Method for preparing chiral amines Method for preparing chiral amines

C - Chemistry, Metallurgy

07

D

C07D 333/36 (2006.01) C07D 311/68 (2006.01) C12P 13/02 (2006.01) C12P 17/04 (2006.01) C12P 17/10 (2006.01)

Patent

CA 2437251

Disclosed is a method of preparing chiral amine. The method includes reacting ketoxime, palladium, lipase, acyl-donating compound, and tertiary amine to prepare amide, and amide is hydrolyzed.

L'invention concerne un procédé de production d'amines chirales. Ce procédé consiste à mettre en réaction un cétoxime, du palladium, une lipase, un composé donneur de groupe acyle et une amine tertiaire afin de préparer un amide, puis à hydrolyser cet amide.

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