N-alkyl-hydroxamic acid-isoindolyl compounds and their...

Details N-alkyl-hydroxamic acid-isoindolyl compounds and their... N-alkyl-hydroxamic acid-isoindolyl compounds and their...

C - Chemistry, Metallurgy

07

D

C07D 209/46 (2006.01) A61K 31/4035 (2006.01) A61K 31/428 (2006.01) A61K 31/472 (2006.01) A61P 25/04 (2006.01) A61P 25/16 (2006.01) A61P 35/00 (2006.01) C07D 209/48 (2006.01) C07D 217/24 (2006.01) C07D 275/06 (2006.01)

Patent

CA 2518513

The invention encompasses novel N-alkyl-hydroxamic acid-isoindolyl compounds of formula (I) with the definition X1-X4, Z1, Z2, R1, R2, R7 and Y according to claim 1, pharmaceutical compositions of these compounds, and methods of using these compounds and compositions for treatment or prevention of various diseases and disorders mediated by PDE4 inhibition, associated with abnormal TNA-alpha levels, and/or mediated by MMP inhibition.

La présente invention a trait à des composés de N-alkyl-acide hydroxamique-isoindolyle, des compositions pharmaceutiques de ces composés, et des procédés d'utilisation de ces composés et compositions pour le traitement ou la prévention de divers maladies et troubles, par exemple, des maladies liées aux phosphodiestérases 4 (PDE4).

Affiliated with

Also associated with

Rating

N-alkyl-hydroxamic acid-isoindolyl compounds and their... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with N-alkyl-hydroxamic acid-isoindolyl compounds and their..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and N-alkyl-hydroxamic acid-isoindolyl compounds and their... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1696409