Alpha-msh therapies for treatment of autoimmune disease

Details Alpha-msh therapies for treatment of autoimmune disease Alpha-msh therapies for treatment of autoimmune disease

A - Human Necessities

61

K

A61K 38/22 (2006.01) A61K 38/10 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2666887

Methods and compositions for the enteral treatment of autoimmune disease such a multiple sclerosis with polypeptide therapeutics. Enteral therapeutics comprise monomeric alpha-MSH polypeptides such as ACTH. Therapeutic formulations of the invention may be used to reduce the incidence or severity of autoimmune disease. For instance methods for the oral treatment of multiple sclerosis with alpha-MSH and ACTH are described.

La présente invention concerne des procédés et des compositions permettant le traitement entérique de maladies auto-immunes, telles que la sclérose multiple, avec des thérapies polypeptides. Les thérapies entériques comprennent des polypeptides alpha-MSH monomères, tels que l'ACTH. Les formulations thérapeutiques de l'invention peuvent être utilisées pour réduire l'incidence ou la sévérité d'une maladie auto-immune. Par exemple, l'invention porte sur des procédés destinés au traitement oral de scléroses multiples avec l'alpha-MSH et l'ACTH.

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