Methods for substrate and inhibitor screening using...

Details Methods for substrate and inhibitor screening using... Methods for substrate and inhibitor screening using...

C - Chemistry, Metallurgy

12

Q

C12Q 1/26 (2006.01) C12Q 1/25 (2006.01) G01N 33/557 (2006.01)

Patent

CA 2539781

The present invention relates to a method of screening compounds for modulation and binding to proteins, in particular proteins that have been immobilized in a monolithic chromatographic stationary phase. The method involves observing the conversion of a substrate to product by the protein and determining a product to substrate ratio. Changes in this ratio in the presence of another compound indicates that the other compound is a modulator of the enzyme. Various applications of this method to compound screening, including high throughput screening formats, are described.

Affiliated with

Also associated with

Rating

Methods for substrate and inhibitor screening using... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods for substrate and inhibitor screening using..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for substrate and inhibitor screening using... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1696841