Transforming growth factor-beta-related molecules and uses...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) C07K 14/495 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2430257

The present invention provides Transforming Growth Factor-Beta-Related (TGF- .beta.-R) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing TGF-.beta.-R polypeptides. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with TGF-.beta.-R polypeptides.

La présente invention concerne des polypeptides associés au facteur de croissance transformant-beta (TGF-.beta.-R) et des molécules d'acide nucléique les codant. L'invention concerne également des agents de liaison sélectifs, des vecteurs, des cellules hôtes, ainsi que des procédés de production de polypeptides TGF-.beta.-R. L'invention concerne également des compositions pharmaceutiques et des méthodes destinées au diagnostic, au traitement, à l'amélioration et/ou à la prévention de pathologies, de troubles et d'états associés aux polypeptides TGF-.beta.-R.

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