Removal of antibodies from blood-derived compositions while...

C - Chemistry – Metallurgy – 12 – N

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C12N 7/06 (2006.01) A61K 35/14 (2006.01) A61K 35/16 (2006.01) A61K 38/46 (2006.01) A61L 2/16 (2006.01) A61M 1/36 (2006.01) C07K 17/00 (2006.01) G01N 33/86 (2006.01)

Patent

CA 2096654

This invention relates to methods of removing undesired antibodies from blood-derived compositions containing both the antibodies and coagulation factors, such that the coagulation factors are substantially retained in the composition. The undesired antibodies may be blood group antibodies. This invention also relates to compositions in which undesired antibodies have been removed and desired coagulation factors are retained. This invention further relates to methods of inactivating virus and removing undesired antibodies from blood-derived compositions containing virus, antibodies and coagulation factors without removing coagulation factors therefrom, and to the resulting compositions.

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