Endometrial genes in endometrial disorders

Details Endometrial genes in endometrial disorders Endometrial genes in endometrial disorders

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2489568

Genetic sequences are identified with expression levels that are upregulated or downregulated in human endometrium during the window of implantation. The endometrial signature of genes during the window of implantation provides diagnostic screening tests for patients with infertility and endometrial disorders, and endometriosis; and for targeted drug discovery for treating implantation-based infertility, other endometrial disorders, and endometrial- based contraception.

L'invention concerne des s~quences g~niques identifi~es dont les niveaux d'expression sont r~gul~s ~ la hausse ou ~ la baisse dans l'endom­tre humain pendant la fenÚtre d'implantation. La signature endom~triale de g­nes pendant la fenÚtre d'implantation permet d'effectuer des tests de criblage diagnostics sur des patientes pr~sentant une inf~condit~, des troubles endom~triaux ou une endom~triose, et permettant de trouver un m~dicament cibl~ pour traiter l'inf~condit~ r~sultant d'une implantation, ou d'autres troubles endom~triaux, et pour la contraception fond~e sur la fonction endom~triale.

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