Nucleic acids encoding human tbc-1 protein and polymorphic...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) C07H 21/04 (2006.01) C07K 16/18 (2006.01) C12N 15/63 (2006.01) C12N 15/85 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2337694

The invention concerns genomic and cDNA sequences of the human TBC-1 Gene. The invention also concerns polypeptides encoded by the TBC-1 gene. The invention also deals with antibodies directed specifically against such polypeptides that are useful as diagnostic reagents. The invention further encompasses biallelic markers of the TBC-1 gene useful in genetic analysis.

La présente invention concerne des séquences génomiques et d'ADN de forme C du gène TBC-1 humain ainsi que des polypeptides codés par le gène TBC-1. L'invention concerne également des anticorps, dirigés spécifiquement contre de tels polypeptides, qui sont utiles en tant que réactifs pour diagnostic. De plus, l'invention porte sur des marqueurs biallèliques du gène TBC-1 qui sont utiles pour l'analyse génétique.

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