Process for the preparation of asenapine and intermediate...

C - Chemistry – Metallurgy – 07 – D

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C07D 491/044 (2006.01) A61K 31/407 (2006.01) A61P 25/24 (2006.01) C07D 207/08 (2006.01)

Patent

CA 2710800

The invention relates to a novel process for the preparation of asenapine, i.e. trans-5-chloro-2-methyl-2,3,3a,12b-- tetrahydro-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole, as well as to novel intermediate products for use in said process.

L'invention porte sur un nouveau procédé de préparation de l'asénapine, à savoir du trans-5-chloro-2-méthyl-2,3,3a,12b-tétrahydro-1H-dibenz[2,3:6,7]oxépino[4,5-c]pyrrole, ainsi que sur de nouveaux produits intermédiaires destinés à être utilisés dans ledit procédé.

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