Pharmaceutical carriers for nanosuspensions

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/34 (2006.01) A61K 9/10 (2006.01) A61K 31/55 (2006.01) A61K 31/553 (2006.01) A61K 47/10 (2006.01) A61K 47/24 (2006.01)

Patent

CA 2172110

The present invention relates to a formulation base for the preparation of a pharmaceutical composition for the intravenous administration of the sparingly soluble staurosporin derivative N-benzoyl-staurosporin. The composition comprises the following preferred components: a) the therapeutic agent N-benzoyl-staurosporin; b) a polyoxyethylene/polyoxypropylene block copolymer; c) ethanol and water as carrier liquids; and d) purified lecithin from soybeans and e) as water-soluble excipients glycerol and sorbitol.

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