Novel ligand and dna thereof

Details Novel ligand and dna thereof Novel ligand and dna thereof

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 1/14 (2006.01) A61P 3/04 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 14/72 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) G01N 33/577 (2006.01) G01N 33/92 (2006.01)

Patent

CA 2450442

A GPR7 ligand having the amino acid sequence represented by SEQ ID NO:1, which is optionally brominated at the N-terminal amino acid residue, or a substantially the same amino acid sequence is useful in developing a receptor- binding assay system with the use of the GPR7 expression system, screening a candidate compound for a drug such as an antiobestic, etc.

Ligand GPR7 dont la séquence aminoacide est représentée par SEQ ID NO:1, éventuellement brominée au niveau du résidu aminoacide à terminaison N, ou présentant une séquence aminoacide sensiblement identique. Ce ligand est utile pour mettre en oeuvre un système permettant de déterminer la fixation à un récepteur ou pour rechercher par criblage un composé candidat pour un médicament, tel que, par exemple, un médicament contre l'obésité.

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