Venlafaxine in the treatment of hypothalamic amenorrhea in...

Details Venlafaxine in the treatment of hypothalamic amenorrhea in... Venlafaxine in the treatment of hypothalamic amenorrhea in...

A - Human Necessities

61

K

A61K 31/135 (2006.01) A61K 31/137 (2006.01) A61K 31/275 (2006.01)

Patent

CA 2167999

This invention provides a method for treating hypothalamic amenorrhea in a non-depressed female mammal by administering to the mammal an effective amount of a hydroxycycloalkanephenethyl amine compound of the following structural formula: Image in which A is a moiety of the formula Image wherein the dotted line represents optional unsaturation; R1 is hydrogen or alkyl; R2 is alkyl; R4 is hydrogen, alkyl, formyl, or alkanol; R5 and R6 are, independently, hydrogen, hydroxyl, alkyl, alkoxy, alkanoyloxy, cyano, nitro, alkylmercapto, amino, alkylamino, dialkylamino, alkanamido, halo, trifluoromethyl, or taken together, methylene dioxy; R7 is hydrogen or alkyl; and n is 0, 1, 2, 3, or 4; or a pharmaceutically acceptable salt thereof.

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