Modified kluyveromyces yeasts, their preparation and use

Details Modified kluyveromyces yeasts, their preparation and use Modified kluyveromyces yeasts, their preparation and use

Category

C - Chemistry, Metallurgy

Subcategory

12

Subsubcategory

N

IPC codes

C12N 15/57 (2006.01) C12N 1/19 (2006.01) C12N 9/48 (2006.01) C12N 9/60 (2006.01) C12N 15/11 (2006.01) C12N 15/81 (2006.01)

Type

Patent

Patent number

CA 2139117

Description

Yeasts of the genus (Kluyveromyces) having one or more genetic modifications of at least one gene encoding a protease, said gene reducing or modifying the proteolytic activity of said yeasts. The invention also concerns the use of said yeasts as host cell for the secretion of recombinant proteins.

2139117 9400579 PCTABS00165 La présente invention concerne des levures du genre Kluyveromyces présentant une ou plusieurs modifications génétiques d'au moins un gène codant pour une protéase, réduisant ou modifiant l'activité protéolytique desdites levures, ainsi que leur utilisation comme cellule hôte pour la sécrétion de protéines recombinantes.

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