Transgenic amorpha-4,11-diene synthesis

Details Transgenic amorpha-4,11-diene synthesis Transgenic amorpha-4,11-diene synthesis

C - Chemistry, Metallurgy

12

N

C12N 15/60 (2006.01) A01H 5/00 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/88 (2006.01) C12N 15/70 (2006.01) C12N 15/82 (2006.01) C12P 5/00 (2006.01) C12P 17/18 (2006.01)

Patent

CA 2340925

The present invention relates to an isolated DNA sequence encoding a polypeptide having the biological activity of amorpha-4,11-diene synthase. This DNA sequence can be used for the transformation of bacteria, yeasts and plants for the production of amorpha-4,11-diene, a specific precursor in the synthesis of artemisinin, in the respective organisms. The invention also relates to these organisms.

La présente invention concerne une séquence d'ADN isolée codant un polypeptide présentant l'activité biologique de l'amorpha-4,11-diène. Cette séquence d'ADN peut être utilisée pour la transformation de bactéries, de levures et de plantes pour la production d'amorpha-4,11-diène, précurseur spécifique de la synthèse de l'artémisine, dans les organismes respectifs. L'invention traite également de ces organismes.

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