Substituted 1,3-dioxanes and their uses

C - Chemistry – Metallurgy – 07 – D

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C07D 319/06 (2006.01) A61K 31/357 (2006.01)

Patent

CA 2676437

The present invention relates to compounds containing 1,3-dioxane moiety, pharmaceutical compositions thereof, and the use of the compounds and compositions for the modulation of thromboxane A2 or a peroxisome proliferator-activated receptor. The compounds, analogs, and pharmaceutically acceptable salts thereof, and pharmaceutical compositions can be used in the treatment and prevention of cancer.

La présente invention concerne des composés contenant un groupe fonctionnel 1,3-dioxane, des compositions pharmaceutiques de ceux-ci, et l'utilisation de ces composés et compositions pour moduler le thromboxane A2 ou un récepteur activé par le proliférateur de peroxysome. Les composés, les analogues, et les sels pharmaceutiquement acceptables de ceux-ci, et les compositions pharmaceutiques peuvent être utilisés dans le traitement et la prévention de cancer.

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