A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 27/54 (2006.01) A61L 27/28 (2006.01) A61L 29/08 (2006.01) A61L 29/16 (2006.01) A61L 31/08 (2006.01) A61L 31/16 (2006.01)
Patent
CA 2466432
The invention relates to an intraluminal device, in particular an intraluminal prosthesis, shunt, catheter or local drug delivery device. In order to increase the bio-compatibility of this device, it is provided with at least one coating. The coating contains a therapeutic agent which is comprised in a matrix that sticks to the intraluminal device. Instead of being formed by a little bio-compatible polymer, the matrix is formed by a bio-compatible oil or fat, such as cod-liver oil or olive oil. Preferably, the bio-compatible oil or fat further comprises alfa-tocopherol.
L'invention concerne un dispositif intraluminal, plus spécifiquement une prothèse intraluminale, un dispositif d'anastomose, un cathéter ou un dispositif d'administration locale de médicament. Ce dispositif comprend, afin d'augmenter sa biocompatibilité, au moins un revêtement. Ce revêtement contient une substance thérapeutique comprise dans une matrice qui colle au dispositif intraluminal. Au lieu d'être formée d'un polymère peu biocompatible, cette matrice est formée d'une huile biocompatible ou d'une graisse biocompatible, telles que de l'huile de foie de morue ou de l'huile d'olive. De préférence, l'huile biocompatible ou la graisse biocompatible comprend également de l'alfa-tocophérol.
de Scheerder Ivan
Dhondt Maria
Jacobs Pierre
Martens Johan
Atrium Medical Corporation
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
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