Methods of screening for trpm4 modulators of insulin secretion

Details Methods of screening for trpm4 modulators of insulin secretion Methods of screening for trpm4 modulators of insulin secretion

C - Chemistry, Metallurgy

12

Q

C12Q 1/02 (2006.01) G01N 33/53 (2006.01) G01N 33/567 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2652960

The invention relates to methods useful in identifying candidate agents that modulate insulin secretion from an insulin secreting cell, where such molecules modulate TRPM4 activity and expression in the insulin secreting cell.

L'invention concerne des méthodes utiles pour l'identification d'agents d'intérêt potentiel qui modulent la sécrétion d'insuline à partir d'une cellule qui sécrète de l'insuline, ces modules modulant l'activité et l'expression de TRPM4 dans la cellule qui sécrète de l'insuline.

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