A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01) C07K 14/47 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2247247
The invention concerns methods of inhibiting atopic angiogenesis using troponin subunits and peptide fragments thereof. The invention further concerns pharmaceutical compositions comprising a troponin subunit or a fragment thereof. The pharmaceutical compositions and the methods of the invention are useful in the treatment of solid tumors, particularly tumors of the central nervous system and of the eye.
Des procédés permettent d'inhiber l'angiogénèse atopique à l'aide de sous-unités de troponine et de leurs fragments peptidiques. On décrit aussi des compositions pharmaceutiques comprenant une sous-unité de troponine ou un de ses fragments. Ces compositions et procédés permettent de traiter des tumeurs solides, particulièrement celles du système nerveux central et de l'oeil.
Langer Robert S.
Moses Marsha A.
Sytkowski Arthur
Wiederschain Dimitri G.
Wu Inmin
Children's Medical Center Corporation
Osler Hoskin & Harcourt Llp
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