A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/353 (2006.01) A61K 31/137 (2006.01) A61K 31/216 (2006.01) A61P 9/00 (2006.01) A61P 9/04 (2006.01)
Patent
CA 2576255
The present invention relates to the use of one or more first compound(s) having a beta3-adrenoceptor agonistic effect and one or more second compound(s) having a beta1/beta2-adrenoceptor antagonistic effect for the preparation of a medicament for treating and/or preventing cardiovascular diseases and diseases related thereto, such as arterial diseases, ischemic and failing cardiac diseases, including heart failure, conditions related to metabolic syndrome, or angiogenesis-related diseases, wherein said one or more first compound(s) and said one or more second compound(s) are used as combined preparation for simultaneous, separate or sequential use. The invention further provides methods and composition for treating the above diseases.
La présente invention porte sur l~utilisation d~un ou de plusieurs premiers composés ayant un effet agoniste bêta 3-adrénocepteur et un ou plusieurs seconds composés ayant un effet antagoniste bêta1/bêta2-adrénocepteur pour la fabrication d~un médicament pour traiter et/ou prévenir les maladies cardiovasculaires et les maladies s~y rapportant, comme les maladies artérielles, l~ischémie et les maladies d~insuffisance cardiaque comme la crise cardiaque, les conditions liées au syndrome métabolique ou les maladies de type angiogène, où ledit ou lesdits premiers composés et ledit ou lesdits seconds composés servent de préparation combinée pour une utilisation simultanée, séparée ou séquentielle. L~invention porte en outre sur des procédés et une composition pour traiter les maladies ci-dessus.
Balligand Jean-Luc
Dessy Chantal
Smart & Biggar
Universite Catholique de Louvain
LandOfFree
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