C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/495 (2006.01) A61P 35/00 (2006.01) C07D 221/00 (2006.01) C07D 239/00 (2006.01)
Patent
CA 2515605
The invention describes compounds of the general formula (I), 5 a process for their manufacture, medicaments containing them and their manufacture as well as the use of these compounds as pharmaceutically active agents. The compounds show activity as protein kinase inhibitors, in particular src family tyrosine kinase inhibitors, and may therefore be usefull for the treatment of diseases mediated by said tyrosine kinases.
L'invention concerne des composés de formule générale (I), un procédé de fabrication associé, des médicaments les contenant et leur fabrication ainsi que l'utilisation desdits composés en tant qu'agents pharmaceutiquement actifs. Lesdits composés présentent une activité en tant qu'inhibiteurs de protéines kinases, en particulier en tant qu'inhibiteurs de tyrosines kinases de la famille Src et peuvent par conséquent être utiles pour le traitement de maladies induites par lesdites tyrosines kinases.
Honold Konrad
Schaefer Wolfgang
Scheiblich Stefan
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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