Complex comprising an igfiie polypeptide-fragment and an...

C - Chemistry – Metallurgy – 07 – K

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C07K 14/65 (2006.01) A61K 38/30 (2006.01) A61P 19/10 (2006.01)

Patent

CA 2387897

A substantially pure complex including IGFIIE polypeptide and IGFBP2 polypeptide is described. Methods for treating an osteoporosis patient and targeting a compound to the skeletal extracellular matrix of a patient are also described.

Cette invention se rapporte à un complexe sensiblement pur, qui contient le polypeptide IGFIIE et le polypeptide IGFBP2, ainsi qu'à des procédés de traitement d'un patient souffrant d'ostéoporose et de ciblage d'un composé sur la matrice extracellulaire du squelette du patient.

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