Expression system for non-secretor genes

Details Expression system for non-secretor genes Expression system for non-secretor genes

C - Chemistry, Metallurgy

12

N

C12N 15/85 (2006.01) A61K 39/00 (2006.01) A61K 39/12 (2006.01) C07K 14/18 (2006.01) C12N 15/67 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01) G01N 33/576 (2006.01)

Patent

CA 2223182

A mammalian expression system capable of generating recombinant proteins from non-secretor genes. Also provided are an assay which utilizes the fusion protein, a test kit which contains the fusion protein, a diagnostic reagent which comprises the fusion protein, and a vaccine which utilizes the fusion protein produced by the disclosed plasmid.

Le système décrit d'expression chez des mammifères permet de générer des protéines recombinées à partir de gènes non sécréteurs. L'invention concerne également un dosage au moyen d'une protéine de fusion, une trousse d'analyse qui contient la protéine de fusion, un réactif de diagnostic qui contient la protéine de fusion, et un vaccin qui utilise la protéine de fusion produite par le plasmide décrit.

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