Stimulation of anti-tumor immunity using dendritic...

Details Stimulation of anti-tumor immunity using dendritic... Stimulation of anti-tumor immunity using dendritic...

C - Chemistry, Metallurgy

12

N

C12N 5/12 (2006.01) A61K 39/00 (2006.01) C12N 5/16 (2006.01) G01N 33/00 (2006.01)

Patent

CA 2704232

The invention is concerned with fusions of dendritic cells and with tumor or cancer cells. Also provided are methods of making and using these cell fusions, including methods of adoptive immunotherapy as well as methods of stimulating anti-tumor immunity using fused cells and anti-CD3/CD28 antibodies.

L'invention concerne des fusions de cellules dendritiques et de cellules présentant un antigène. Il est également proposé des procédés de fabrication et d'utilisation de ces fusions cellulaires, y compris des procédés d'immunothérapie adoptive de même que des procédés de stimulation de l'immunité anticancéreuse à l'aide de cellules fusionnées et d'anticorps anti-CD3/CD28.

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