N-alkyl phenylcarboxamide beta-secretase inhibitors for the...

Details N-alkyl phenylcarboxamide beta-secretase inhibitors for the... N-alkyl phenylcarboxamide beta-secretase inhibitors for the...

C - Chemistry, Metallurgy

07

C

C07C 311/04 (2006.01) A61K 31/16 (2006.01) A61K 31/18 (2006.01) A61K 31/275 (2006.01) A61K 31/40 (2006.01) A61K 31/495 (2006.01) A61K 31/50 (2006.01) C07C 233/05 (2006.01) C07C 255/50 (2006.01) C07D 207/04 (2006.01) C07D 241/04 (2006.01)

Patent

CA 2529994

The present invention is directed to compounds which are inhibitors of the beta-secretase enzyme and which are useful in the treatment or prevention of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.

La présente invention concerne des composés inhibiteurs de la .beta.-sécrétase et convenant au traitement ou à la prévention d'affections en liens avec la .beta.-sécrétase, et notamment la maladie d'Alzheimer. L'invention concerne également des compositions pharmaceutiques comprenant ces composés et l'utilisation de ces composés et composition pour le traitement de telles affections en liens avec la .beta.-sécrétase.

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