A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/506 (2006.01) A61P 25/28 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2580976
This invention relates to the use of 4-(4-methylpiperazin-l-ylmethyl)-N-[4- methyl-3-(4-pyridin-3-yl)pyrimidin-2- ylamino)phenyl]-benzamide, (also known as imatinib, gleevec, glivec, cgp57148b or 8TI571), or a pharmaceutically acceptable salt thereof, for the manufacture of a medicament for the treatment of c-fms associated diseases including; choriocarcinoma, malignant histiocytosis, embryonal carcinoma, endometrial carcinoma, brain microglial tumours, sarcoidosis, microglial cell involvement in normal and variant Creutzfeld- Jacob disease, and amyotrophic lateral sclerosis.
La présente invention décrit l~emploi du 4-(4-méthylpiperazin-1-ylméthyl)-N-[4-méthyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phényl]benzamide (aussi connu sous les appellations suivantes : imatinib, gleevec, glivec, cgp57148b ou STI571) ou d~un sel de qualité pharmaceutique de ce composé, dans la fabrication d~un médicament servant au traitement des maladies liées au c-fms. Lesdites maladies incluent : chorio-épithéliomes, histiocytose maligne, carcinomes embryonnaires, carcinomes de l~endomètre, tumeurs microgliales cérébrales, sarcoïdose, implication des cellules microgliales dans la maladie de Creutzfeld-Jacob ordinaire et dans sa variante, et sclérose latérale amyotrophique.
Dewar Andrea Louise
Hughes Timothy Peter
Lyons Alan Bruce
Fetherstonhaugh & Co.
Medvet Science Pty Ltd
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