Protected amino acids and process for the preparation thereof

Details Protected amino acids and process for the preparation thereof Protected amino acids and process for the preparation thereof

C - Chemistry, Metallurgy

07

C

260/317, 530/7.0

C07C 237/06 (2006.01) C07C 271/22 (2006.01) C07D 253/08 (2006.01) C07K 1/06 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01)

Patent

CA 2014491

4-17556/1+2/+ Protected amino acids and process for the preparation thereof Abstract Compounds of the formula I, Image (I) in which n stands for 1 or 2, R1 denotes hydrogen or an amino protective group, R2 denotes hydrogen or a carboxyl protective group and R3 denotes triphenylmethyl, 4-monomethoxy-trityl or 4,4'-dimethoxy-trityl, and reactive carboxylic acid derivatives of such compounds of the formula I in which R2 stands for hydrogen, are described. These compounds can be used as starting materials for the preparation of peptides. They are more suitable for this than are analogous compounds of the formula I in which R3 denotes hydrogen or one of the carbamoyl protective groups hitherto customary.

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