Pyrimidine-2,4,6-trione metalloproteinase inhibitors

Details Pyrimidine-2,4,6-trione metalloproteinase inhibitors Pyrimidine-2,4,6-trione metalloproteinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 239/62 (2006.01) A61K 31/505 (2006.01) A61P 35/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2425280

The present invention relates to pyrimidine-2,4,6-trione metalloproteinase inhibitors of the formula (I) wherein X, Y, A, B and R1 are as defined in the specification, and to pharmaceutical compositions and methods of treating inflammation, cancer and other disorders.

La présente invention concerne des inhibiteurs de la pyrimidine-2,4,6-trione métalloproteinase de formule (I), dans laquelle X, Y, A, B et R?1¿ sont définis comme dans la description, ainsi que des compositions pharmaceutiques et des méthodes de traitement d'inflammations, de cancers et autres troubles.

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