C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07H 21/00 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C12P 19/34 (2006.01)
Patent
CA 2496182
The present invention describes terminal phosphate blocked nucleoside polyphosphates that are stable at high temperature and their use in nucleic acid amplification and analysis. Current invention further describes charge modified terminal phosphate blocked nucleoside polyphosphates for improved incorporation and direct loading of nucleic acid sequencing reactions onto separating media.
L'invention a trait à des polyphosphates de nucléoside à phosphate terminal bloqué qui sont stables à température élevée, et à leur utilisation dans l'amplification et l'analyse d'acide nucléique. L'invention concerne de plus des polyphosphates de nucléoside à phosphate terminal bloqué dont la charge a été modifiée, qui permettent une incorporation améliorée et un chargement direct de réactions de séquençage d'acide nucléique sur des milieux de séparation.
Fuller Carl
Kumar Shiv
Nelson John
Sood Anup
Amersham Biosciences Corp
Fetherstonhaugh & Co.
Ge Healthcare Bio-Sciences Corp.
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