Methods and systems for treating bph using electroporation

A - Human Necessities – 61 – N

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A61N 1/00 (2006.01) A61B 18/04 (2006.01)

Patent

CA 2612530

A system for treating benign prostate hyperplasia (BPH) of a prostate. At least first and second mono-polar electrodes are configured to be introduced at or near a BPH tissue site of the prostate gland of the patient. A voltage pulse generator is coupled to the first and second mono-polar electrodes. The voltage pulse generator is configured to apply sufficient electrical pulses between the first and second mono-polar electrodes to induce electroporation of cells in the BPH tissue site, to create necrosis of cells of the BPH tissue site, but insufficient to create a thermal damaging effect to a majority of the BPH tissue site.

L'invention concerne un système destiné à traiter l'hyperplasie bénigne de la prostate (BPH) chez un patient. Au moins une première et une seconde électrodes monopolaires sont configurées pour être introduites dans ou à proximité d'un site du tissu BPH de la glande prostatique du patient. Un générateur d'impulsions électriques est couplé aux électrodes monopolaires et configuré pour appliquer entre la première et la seconde électrodes monopolaires des impulsions électriques suffisantes pour déclencher dans le site du tissu BPH une électroporation de cellules pouvant provoquer la nécrose de cellules du site du tissu BPH, mais insuffisantes pour créer un effet thermique destructeur sur la majeure partie du site du tissu BPH.

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