Fibrinogen receptor antagonists

Details Fibrinogen receptor antagonists Fibrinogen receptor antagonists

A - Human Necessities

61

K

A61K 38/00 (2006.01) A61K 38/05 (2006.01) C07C 229/00 (2006.01) C07C 237/22 (2006.01) C07C 311/19 (2006.01) C07C 323/00 (2006.01) C07D 295/15 (2006.01)

Patent

CA 2322743

Compounds of this invention have the formula: X-(CH2)n-C(O)NH-A-C(COOR5)R3R4 or a pharmaceutically acceptable salt thereof, e.g. formula (1-7) which are useful for inhibiting fibrinogen binding to blood platelets, thereby inhibiting platelet aggregation.

L'invention concerne des composés représentés par la formule X-(CH¿2?)¿n?-C(O)NH-A-C(COOR?5¿)R?3¿R?4¿ ou un sel pharmaceutiquement acceptable de ceux-ci représenté par la formule (1-7). Ces composés sont utiles pour inhiber un fibrogène se liant aux plaquettes sanguines, inhibant de ce fait une agrégation de plaquettes.

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