Methods for identifying inhibitors of integrin activation

Details Methods for identifying inhibitors of integrin activation Methods for identifying inhibitors of integrin activation

C - Chemistry, Metallurgy

07

K

C07K 14/705 (2006.01) C07K 16/28 (2006.01) C07K 19/00 (2006.01) C12Q 1/02 (2006.01) G01N 33/554 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2185446

The invention features a method for inhibiting the ligand binding of an integrin in a cell involving introducing into the cell a compound which inhibits integrin activation, a method for identifying compounds which inhibit integrin activation, and chimeric integrin molecules.

Procédé inhibant la fixation de ligands de l'intégrine d'une cellule consistant à introduire dans la cellule un composé inhibant l'activation de l'intégrine, et procédé d'identification de composés inhibant l'activation de l'intégrine et les molécules chimères d'intégrine.

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