Polymorphs of an epothilone analog

Details Polymorphs of an epothilone analog Polymorphs of an epothilone analog

C - Chemistry, Metallurgy

07

D

C07D 491/04 (2006.01) A61K 31/425 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2418109

There are provided in accordance with the present invention two crystalline polymorphs, designated Form A and Form B, respectively, as well as mixtures thereof, of an epothilone analog represented by formula (I). Also provided are methods of forming the novel polymorphs, therapeutic methods utilizing them and pharmaceutical dosage forms containing them.

L'invention porte sur deux polymorphes cristallins, dits Forme A et Forme B, et leur mélange, consistant en en analogues d'épothilone de formule (I), sur les procédés d'obtention desdits polymorphes, sur des procédés thérapeutiques les utilisant, et sur des formes posologiques pharmaceutiques les contenant.

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