A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/437 (2006.01) A61K 45/06 (2006.01)
Patent
CA 2732636
The present invention relates to a pharmaceutical composition comprising gaboxadol or a pharmaceutically accept-able salt thereof and one or more inhibitors of PAT1 and/or one or more inhibitors of OAT. The present invention further relates to a pharmaceutical composition comprising from about 0.5 mg to about 50 mg gaboxadol or a pharmaceutically acceptable salt thereof, wherein the composition provides an in vivo plasma profile comprising a mean Tmax which is longer than about 20 minutes.
La présente invention concerne une composition pharmaceutique comprenant du gaboxadol ou un sel pharmaceutiquement acceptable de ce dernier ainsi qu'un ou plusieurs inhibiteurs de PAT1 et/ou un ou plusieurs inhibiteurs d'OAT. La présente invention concerne en outre une composition pharmaceutique comprenant entre environ 0,5 mg et environ 50 mg de gaboxadol ou d'un sel pharmaceutiquement acceptable de ce dernier, la composition présentant un profil plasmatique in vivo comprenant un Tmax moyen supérieur à environ 20 minutes.
Holm Rene
Larsen Birger Brodin
Larsen Mie
Nielsen Carsten Uhd
Goudreau Gage Dubuc
H. Lundbeck A/s
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