Stereoselective process for preparing .beta.-anomer enriched...

Details Stereoselective process for preparing .beta.-anomer enriched... Stereoselective process for preparing .beta.-anomer enriched...

C - Chemistry, Metallurgy

07

H

C07H 19/173 (2006.01) C07H 11/00 (2006.01) C07H 13/00 (2006.01) C07H 13/08 (2006.01) C07H 19/14 (2006.01) C07H 19/16 (2006.01)

Patent

CA 2130618

A stereoselective process for preparing a .beta.- anomer enriched 2-deoxy-2,2-difluoro-D-ribofuranosyl-3,5- hydroxy protected-1-alkyl and aryl sulfonate intermediates by contacting an .alpha.-anomer enriched 2-deoxy-2,2-difluoro-D- ribofuranosyl-3,5-hydroxy protected-1-fluoroalkyl and fluoroaryl sulfonate with a conjugate anion of a sulfonic acid containing the desired alkyl or aryl sulfonate.

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