Traits in recombinant xylose-growing saccharomyces...

Details Traits in recombinant xylose-growing saccharomyces... Traits in recombinant xylose-growing saccharomyces...

C - Chemistry, Metallurgy

12

N

C12N 1/19 (2006.01) C12P 7/06 (2006.01)

Patent

CA 2560894

New xylose-utilizing Saccharomyces cerevisiae strain which can ferment xylose to ethanol. It expresses the gene for A) xylose reductase (XR) and Xylitol dehydrogenase (XDH) or B) xylose isomerase (XI) and has a) increased transporting capacity with regard to xylose, b) increased conversion capacity of xylulose to xylulose-5P, c) increased activity of the oxidative pentose phosphate pathway, and/or d) increased activity of the non-oxidative pentose phosphate pathway.

Une nouvelle souche de Saccharomyces cerevisiae utilisant le xylose par l'expression des gènes de xylose-réductase (XR-XDH) ou de xylose-isomérase (XI) permet d'obtenir de l'éthanol, par fermentation du xylose, mieux que la souche témoin; elle présente en outre: a) une meilleure capacité de transport quant au xylose, b) une meilleure capacité de conversion de xylulose en xylulose-5P, c) une activité accrue du processus pentose phosphate oxydatif, et/ou, d) une activité accrue du processus pentose phosphate non oxydatif.

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