Methods to identify factors associated with muscle growth...

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) A01K 67/027 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01) C12Q 1/00 (2006.01)

Patent

CA 2644057

The present invention relates to methods to identify factors associated with muscle growth, angiogenesis, obesity, insulin sensitivity body weight, fat mass, muscle mass and cardiovascular ftinction. In particular, the methods of the present invention relates to assays to identify such factors using a transgenic animal model and/or a cell-based assay.

L'invention concerne des procédés permettant d'identifier des facteurs associés à la croissance musculaire, l'angiognèse, l'obésité, le poids corporel sensible à l'insuline, la masse adipeuse, la masse musculaire, et la fonction cardiovasculaire. Plus précisément, ces procédés concernent des dosages permettant d'identifier de tels facteurs faisant appel à un modèle animal transgénique et/ou un dosage à base cellulaire.

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