Semi-permeable compositions providing reduced drying time...

Details Semi-permeable compositions providing reduced drying time... Semi-permeable compositions providing reduced drying time...

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 9/22 (2006.01) A61K 9/32 (2006.01) A61K 9/36 (2006.01)

Patent

CA 2613357

Disclosed are methods including providing an osmotic core; coating the osmotic core with a coating composition that comprises cellulose acetate butyrate; drying the coated osmotic core for a maximum period of about 36 hours; wherein the coated core is dried to an average residual solvent content of less than about 1000 parts per million. Also disclosed are coated osmotic cores and methods of administering the coated osmotic cores to a patient.

L'invention concerne des procédés comprenant les étapes qui consistent : à fournir un noyau osmotique ; à revêtir ce noyau osmotique à l'aide d'une composition de revêtement qui renferme de l'acétobutyrate de cellulose ; à sécher le noyau osmotique ainsi revêtu pendant une période maximale d'approximativement 36 heures, ledit noyau étant séché jusqu'à ce qu'il présente une teneur moyenne en solvant résiduel inférieure à approximativement 1000 parts par million. La présente invention se rapporte en outre à des noyaux osmotiques revêtus, ainsi qu'à des procédés pour administrer ces noyaux osmotiques revêtus à un patient.

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