Hydrindane analogs having sphingosine 1-phosphate receptor...

Details Hydrindane analogs having sphingosine 1-phosphate receptor... Hydrindane analogs having sphingosine 1-phosphate receptor...

C - Chemistry, Metallurgy

07

C

C07C 215/38 (2006.01) A61K 31/404 (2006.01) A61K 31/4245 (2006.01) A61P 19/00 (2006.01) A61P 37/00 (2006.01) C07C 233/18 (2006.01) C07D 209/16 (2006.01) C07D 271/06 (2006.01) C07D 333/20 (2006.01) C07D 413/04 (2006.01) C07F 9/117 (2006.01)

Patent

CA 2669104

Hydrindane analogs of formula (IA) and (IB) that have agonist activity at one or more of the SlP receptors are provided. The ' compounds are sphingosine analogs, which, after phosphorylation, can behave as agonists at SlP receptors.

La présente invention concerne des analogues d'hydrindane ayant une activité agoniste à un ou plusieurs récepteurs S1P. Les composés sont des analogues de sphingosine, qui, après phosphorylation, peuvent se comporter comme agonistes de récepteurs S1P.

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