3-substituted pyridine derivatives as h3 antagonists

Details 3-substituted pyridine derivatives as h3 antagonists 3-substituted pyridine derivatives as h3 antagonists

C - Chemistry, Metallurgy

07

D

C07D 213/82 (2006.01) A61K 31/496 (2006.01) A61P 1/00 (2006.01) C07D 213/83 (2006.01)

Patent

CA 2588463

The present invention relates to compounds of formula (I), wherein R1, R2 and A are as defined in the description and claims, and pharmaceutically acceptable salts thereof as well as to pharmaceutical composition comprising these compounds and to methods for their preparation. The compounds are useful for the treatment and/or prevention of diseases which are associated with the modulation of H3 receptors.

La présente invention a pour objet des composés de formule (I), où R1, R2 et A sont tels que définis dans la description et les revendications, ainsi que des sels de qualité pharmaceutique de ces composés, de même que des préparations pharmaceutiques incluant ces composés et des méthodes de préparation de ces composés. Lesdits composés peuvent être employés dans le traitement prophylactique et/ou thérapeutique de maladies liées à la modulation des récepteurs H3.

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